据意大利《共和国报》网站1月11日报道,意大利米兰大学牵头的一项国际研究团队在2019年11月10日的一例呈皮肤炎症状的25岁女性患者的活检样本中,发现了新冠病毒基因序列。这一结果将意大利“零号病人”出现时间再次提前到2019年11月。
图源:CGTN
An international research team led by the University of Milan in Italy discovered the gene sequence of COVID from a biopsy sample of a young female patient with skin disease in the country on Nov 10, 2019, according to Italian media outlet ANSA and news website the Republic. This result has moved the appearance of "patient zero" in Italy to November 2019.
该研究结果被发表在《英国皮肤病学杂志》上。研究人员对2019年最后几个月内没有得到确诊的非典型皮肤病患者活检样本进行了检测,发现该患者感染新冠病毒后唯一的症状是皮肤出现了红色斑块并有轻微喉咙疼痛。此外,该患者在2020年6月的一次血清检测中,检出新冠病毒抗体。米兰大学研究人员认为,这是目前发现的最早人类感染新冠病毒病例。
图源:CGTN
The results were published in the British Journal of Dermatology. The researchers tested biopsy samples from a patient with atypical skin disease who had not been diagnosed in the last few months of 2019 and found the patient was infected with COVID. Her symptoms were only red patches on her skin and a mild sore throat. In addition, the patient was positive for antibodies to COVID in a serum test taken in June. Researchers from the university believe this is the earliest coronavirus infection found in Italy.
该研究团队牵头人、来自米兰大学的贾诺蒂向媒体表示,在接下来的研究中,可能还会发现比2019年11月更早的新冠病毒感染样本。他说,研究发现一些感染新冠病毒的病例只表现出皮肤病症状,因此他们想知道在新冠肺炎疫情暴发前的皮肤病患者中是否有人已经感染了新冠病毒。
Janotti, from the University of Milan and leader of the research team, told media in the next study, new coronavirus infection samples may be found from earlier than November 2019. He said the study found some cases showed only skin symptoms, so they wanted to know whether any skin disease patients before the outbreak had been infected.
随着研究深入,此前已有多项研究表明,多国出现早期新冠肺炎确诊病例的时间再次提前。
研究人员已在意北部城市米兰和都灵2019年12月的城市废水样本中检测到新冠病毒。2020年11月,意大利米兰国家肿瘤研究所等机构研究人员在该国《肿瘤杂志》上发表论文说,新冠病毒可能早在2019年9月就已在意大利传播,这比意大利报告首例新冠肺炎确诊病例早了几个月。
图源:CGTN
Previously, researchers had detected the coronavirus in municipal wastewater samples from the northern cities of Milan and Turin in December 2019. In November 2020, researchers from the National Institute of oncology and other institutions in Milan, published a paper in the National Journal of oncology, saying that the coronavirus may have spread in Italy as early as September 2019, a few months earlier than the first confirmed case of COVID reported in Italy.
综合来源:中国日报 CGTN 人民日报海外网 央视新闻